Closed Loop System

The artificial beta cell or closed-loop insulin delivery system expands on the concept of sensor responsive insulin delivery. The closed-loop system differs from conventional pump therapy as the former uses a control algorithm that autonomously and continually increases and decreases the subcutaneous delivery of insulin on the basis of real-time sensor glucose levels. There have been extensive studies in a controlled laboratory setting of a closed system; however, the real challenge sets in when the same device is used by patients at home. A study published in the New England…